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Furthermore, the indole core is substituted at R3 which has a carbonyl team which is also bonded to some napthalene moeity. Napthalene is often a bicyclic structure of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it to be a ketone. JWH-018 is definitely an analog of THJ-018, wherein the Main indazole structure is substituted